Regulation of amyloid precursor protein processing by its KFERQ motif
نویسندگان
چکیده
منابع مشابه
Regulation of amyloid precursor protein processing by its KFERQ motif
Understanding of trafficking, processing, and degradation mechanisms of amyloid precursor protein (APP) is important because APP can be processed to produce β-amyloid (Aβ), a key pathogenic molecule in Alzheimer's disease (AD). Here, we found that APP contains KFERQ motif at its C-terminus, a consensus sequence for chaperone-mediated autophagy (CMA) or microautophagy which are another types of ...
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ژورنال
عنوان ژورنال: BMB Reports
سال: 2016
ISSN: 1976-6696
DOI: 10.5483/bmbrep.2016.49.6.212